Division of General Internal Medicine

Presented at the
11th Annual Update in Primary Care
October 8-10, 1998, Landmark Resort, Egg Harbor, WI


Diabetic Nephropathy


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Table of Contents

Diabetic Nephropathy

Diabetic Nephropathy in Type 1 and Type 2 diabetes

Diabetic Nephropathy

Definition of abnormal albumin excretion

Definition of Microalbuminuria

Prevalence of Diabetic Nephropathy

Cost

Risk factors

Natural History of Diabetic Nephropathy

Differences between Type 1 and Type 2 diabetes

Screening

False Positives

Measurements

Prevention

Glycemic Control

Glycemic control in Type 2 diabetes - Kumamoto Study

Glycemic threshold?

ACE Inhibitors

Normotensive Type 2 Diabetics

Microalbuminuria and ACE Inhibitors

Treatment of Overt Diabetic Nephropathy

Blood Pressure Control

Decline in GFR

ACE inhibitors

Calcium Channel Blockers

Blood Pressure Goals

Protein restriction

Can Diabetic Nephropathy be reversed?

Future treatments

Summary

 Author: Rick Gillis, MD

Email: rgillis@mcw.edu

General Internal Medicine
9200 W. Wisconsin Ave.
Milwaukee, WI. 53226
Last Update: 10/13/98.